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<title>Dr. Mariano Pirozzo — Neurosurgery</title>
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<description>A publication on the neurosurgery of today and tomorrow.</description>
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<title>Minimally invasive, maximally considered</title>
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<category>Journal</category>
<description>Most back pain never needs surgery. The cases that do are operated differently today: less muscle cut, shorter stays and better patient selection.</description>
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<title>When surgery uses no scalpel</title>
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<category>Journal</category>
<description>Hundreds of radiation beams, one millimetric point, no incision. Radiosurgery forces us to rethink what &#x27;operating&#x27; means.</description>
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<title>Time is brain</title>
<link>https://mpirozzo.com/en/journal/stroke-time-is-brain/</link>
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<category>Journal</category>
<description>An ischaemic stroke costs two million neurons a minute. How that race is won, and why it is only won if the patient gets there in time.</description>
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<title>A deep tumor, without opening the skull</title>
<link>https://mpirozzo.com/en/cases/deep-tumor-endoscopy/</link>
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<category>Cases</category>
<description>Why the endonasal route changed the risk calculus in midline lesions, and what the endoscope reaches that the microscope could not see.</description>
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<title>Treating hydrocephalus without leaving anything behind</title>
<link>https://mpirozzo.com/en/cases/hydrocephalus-ventriculostomy/</link>
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<category>Cases</category>
<description>Creating a new natural drainage pathway instead of implanting a permanent shunt.</description>
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<title>The end of a pain that seemed incurable</title>
<link>https://mpirozzo.com/en/cases/trigeminal-neuralgia-decompression/</link>
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<category>Cases</category>
<description>Trigeminal neuralgia: when the cause is a vessel, the answer is not a lifelong drug.</description>
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<title>Brain tumour and meningioma</title>
<link>https://mpirozzo.com/en/patients/brain-tumour-meningioma/</link>
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<category>For patients</category>
<description>How many brain tumours are benign, what happens with a meningioma found by chance, and when surgery beats continued monitoring.</description>
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<title>Cervical disc herniation and numbness in the hands</title>
<link>https://mpirozzo.com/en/patients/cervical-disc-hand-numbness/</link>
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<category>For patients</category>
<description>Why the hand goes numb, how many people improve without surgery, what cervical myelopathy is and which signs mean being seen quickly. Explained for patients.</description>
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<title>Epilepsy that medication does not control</title>
<link>https://mpirozzo.com/en/patients/drug-resistant-epilepsy/</link>
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<category>For patients</category>
<description>What drug-resistant epilepsy means, what the randomised trials showed about surgery, the real risks, and why referral arrives so late.</description>
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<title>A blow to the head</title>
<link>https://mpirozzo.com/en/patients/head-injury/</link>
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<category>For patients</category>
<description>Warning signs after a blow to the head in adults, children and older people. Why the myth about not letting them sleep is false, and how long to keep watch.</description>
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<title>Hydrocephalus</title>
<link>https://mpirozzo.com/en/patients/hydrocephalus/</link>
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<category>For patients</category>
<description>What enlarged ventricles mean, when it is hydrocephalus and when it is not, how a shunt works and what to expect. For babies and older adults.</description>
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<title>Lumbar herniated disc and sciatica</title>
<link>https://mpirozzo.com/en/patients/lumbar-herniated-disc/</link>
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<category>For patients</category>
<description>How many herniated discs resorb on their own, how many need surgery, which warning signs cannot wait, and what to ask at the appointment.</description>
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<title>Lumbar spinal stenosis</title>
<link>https://mpirozzo.com/en/patients/lumbar-spinal-stenosis/</link>
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<category>For patients</category>
<description>Why the legs hurt on walking and settle on sitting, what “severe stenosis” in the report means, and when surgery is needed and when it is not.</description>
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<title>Your baby&amp;#x27;s misshapen head</title>
<link>https://mpirozzo.com/en/patients/misshapen-head-in-babies/</link>
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<category>For patients</category>
<description>How to tell a flat head from posture apart from craniosynostosis, what the only randomised trial says about helmet therapy, and when surgery is needed.</description>
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<title>My hands go numb</title>
<link>https://mpirozzo.com/en/patients/numbness-in-the-hands/</link>
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<category>For patients</category>
<description>Which fingers go numb with each trapped nerve, how much tingling really is carpal tunnel, and what the evidence says about splints and surgery.</description>
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<title>My hand shakes</title>
<link>https://mpirozzo.com/en/patients/tremor-in-the-hands/</link>
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<category>For patients</category>
<description>How essential tremor is told apart from Parkinson&#x27;s, what treatments exist, and what deep brain stimulation and focused ultrasound really deliver.</description>
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<title>Trigeminal neuralgia</title>
<link>https://mpirozzo.com/en/patients/trigeminal-neuralgia/</link>
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<category>For patients</category>
<description>Why it is mistaken for a dental problem, what actually causes it, which treatments work and in what order. Written for patients by a neurosurgeon.</description>
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<title>Unruptured brain aneurysm</title>
<link>https://mpirozzo.com/en/patients/unruptured-brain-aneurysm/</link>
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<category>For patients</category>
<description>The real risk of rupture by size and location, when treating beats watching, and how much ordinary life you can carry on with. With the figures.</description>
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<title>The 4K-3D exoscope</title>
<link>https://mpirozzo.com/en/technology/4k-3d-exoscope/</link>
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<category>Technology</category>
<description>It swaps the microscope&#x27;s eyepieces for a screen the whole theatre can see: what it genuinely improves, and what patient outcome it does not change.</description>
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<title>Artificial intelligence</title>
<link>https://mpirozzo.com/en/technology/artificial-intelligence/</link>
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<category>Technology</category>
<description>Link by link, what artificial intelligence actually does today along a neurosurgical patient&#x27;s path, and where all it measures is speed.</description>
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<title>5-ALA fluorescence</title>
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<category>Technology</category>
<description>The patient drinks a compound and the tumour glows pink under violet light. Almost everything that glows is tumour; the problem is what does not.</description>
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<title>Intraoperative imaging</title>
<link>https://mpirozzo.com/en/technology/intraoperative-imaging/</link>
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<category>Technology</category>
<description>An MRI inside the operating room confirms whether tumour remains: it doubles complete resections, and also the time and the infection risk.</description>
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<title>Neuronavigation and tractography</title>
<link>https://mpirozzo.com/en/technology/neuronavigation-tractography/</link>
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<category>Technology</category>
<description>Navigation locates the tumour to within millimetres. The problem is that the brain, once the dura is opened, stops being where the image says.</description>
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<title>Neurophysiological monitoring</title>
<link>https://mpirozzo.com/en/technology/neurophysiological-monitoring/</link>
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<category>Technology</category>
<description>Electrodes that watch the cord while you operate: it rules out very well, detects poorly, and no randomised trial will ever measure it.</description>
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<title>Adaptive deep brain stimulation</title>
<link>https://mpirozzo.com/en/future/adaptive-deep-brain-stimulation/</link>
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<category>The future</category>
<description>Deep brain stimulation that adjusts its own output in real time: what it promises, what has been proved, and what evidence is still missing.</description>
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<item>
<title>Brain-computer interfaces</title>
<link>https://mpirozzo.com/en/future/brain-computer-interfaces/</link>
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<category>The future</category>
<description>An implant that reads the cortex and turns it into words: what has left the laboratory, for how many patients worldwide, and what scaling would take.</description>
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<title>Digital twins</title>
<link>https://mpirozzo.com/en/future/digital-twins/</link>
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<category>The future</category>
<description>A computational replica of the patient to rehearse the procedure before touching them: how much has reached the clinic and how much is still an idea.</description>
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<title>Focused ultrasound</title>
<link>https://mpirozzo.com/en/future/focused-ultrasound/</link>
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<category>The future</category>
<description>A thousand ultrasound beams cross the skull and ablate a point a few millimetres across: what it is good for today, on what evidence, within what limits.</description>
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<title>New biomarkers</title>
<link>https://mpirozzo.com/en/future/new-biomarkers/</link>
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<category>The future</category>
<description>Blood tests that help decide on a scan after a head injury and detect Alzheimer&#x27;s pathology: what they measure and what they do not decide.</description>
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<title>Personalized medicine</title>
<link>https://mpirozzo.com/en/future/personalized-medicine/</link>
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<category>The future</category>
<description>Since 2021 the diagnosis of a brain tumour includes its molecular biology. What that changed in surgery, and what it has not yet changed in survival.</description>
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<title>Surgical artificial intelligence</title>
<link>https://mpirozzo.com/en/future/surgical-artificial-intelligence/</link>
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<category>The future</category>
<description>More than a thousand authorised AI devices and almost no randomised trial: the distance between being cleared for use and being clinically validated.</description>
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<title>Surgical robotics</title>
<link>https://mpirozzo.com/en/future/surgical-robotics/</link>
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<category>The future</category>
<description>Where the robot is already the normal way to operate, what millimetres and minutes it really gains, and why patient benefit remains undemonstrated.</description>
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